Having Measured a 3-rotor with the idea of getting something like this to work, it could definitely work with a 2-rotor. There would be a couple of insignificant, and very easy things that would need to be done. One, would be custom axles, and a custom intermediate shaft bracket.... no biggie if you have the skill to pull this swap off. Also, you'd have to build an adapter plate for a tranny. your benefit, is that since it spins a proper direction, you could literally shoose from almost any tranny you wanted to use in any car... after all, you have to make new mounts for it all anyway...
The biggest drawback to this car, would be that it'd be for fun only... there are no sanctioning bodies out there that are pleasant to cars that have motors in them from other manufacturers (unless it is an older toyota with a rotary in it, and rwd... lol!).
If you can -seriously- fabricate/weld, and are comfortable with it, then i'd say go for it........ however, if you were that comfortable with it, then you probably wouldn't have asked the question in the first place.... but i'll still try to answer it anyway. lol!